Online First Nr91

Psychiatr. Pol. ONLINE FIRST Nr 91: 1–17

Published ahead of print 31 January 2018

DOI: https://doi.org/10.12740/PP/OnlineFirst/81103

Ewelina Gulas, Grzegorz Wysiadecki, Dominik Strzelecki,
Oliwia Gawlik-Kotelnicka, Michał Polguj

FREE POLISH FULLTEXT:
Jak mikrobiologia może wpływać na psychiatrię? Powiązania między florą bakteryjną jelit a zaburzeniami psychicznymi

FREE ENGLISH FULLTEXT:
Can microbiology affect psychiatry? A link between gut microbiota and psychiatric disorders

Summary
Every single human consists of thousands of genes, billions of neurons and trillions of bacteria. There is a rapidly growing number of data that links the gut microbiome to the development and functioning of the central nervous system, which is a currently proposed paradigm shift in neuroscience. Knowledge on the relationship between gut microbiota and mental disorders is constantly increasing. This phenomenon is known as “gut-brain axis”. The strongest evidence for the role of microbes in the gut-brain axis comes from animal studies. Nevertheless, the gut-brain crosstalk is a bidirectional communication system that not only provides gastrointestinal homeostasis, but can also affect motivation as well as higher cognitive functions. Moreover, gut microbiome can be associated with obesity and inflammatory gastrointestinal disorders. According to the recent studies, there is a link between the composition of gut microbiota and mental disorders in animals (response to depression and chronic stress). This subject requires further examination, especially taking into consideration
potential therapeutic options.

ISSN 0033-2674 (PRINT)

ISSN 2391-5854 (ONLINE)


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