Biological factors and consequences of pregnancy-related anxiety – What do we know so far?
More details
Hide details
Zakład Psychoterapii i Chorób Psychosomatycznych, Katedra Psychiatrii, Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu
Submission date: 2021-04-06
Final revision date: 2021-10-25
Acceptance date: 2021-11-22
Online publication date: 2022-12-31
Publication date: 2022-12-31
Corresponding author
Agata Mikolajkow   

Department and Clinic of Psychiatry, Wroclaw Medical University
Psychiatr Pol 2022;56(6):1289-1314
This review aims to sum up the current knowledge about biological factors of pregnancy related anxiety (PrA) and the most common consequences for both mother and child, thereby identifying the most crucial concerns and suggesting the course of further research in this field. We pursued a literature review using PubMed. Scientists have shown a significant connection between prenatal anxiety and hormonal changes. These alterations include HPA-axis regulation, thyroid function, oxytocin, prolactin, and progesterone levels. PrA is proven to be a multifactorial condition. Several psychological factors correlate with it, e.g., insufficient social support, unplanned pregnancy, lack of physical activity, and a high level of distress. Although pregnancy is a significant change in one’s life and may be a stressful event, it seems inadequate to believe that clinically relevant prenatal anxiety should be explained only by these psychological factors. Pregnancy-related anxiety is a common mental health disorder in pregnancy, and further studies are needed to minimize the risk of its severe consequences.
Journals System - logo
Scroll to top