PL EN
Vitamin D deficiency and depressive symptoms: meta-analysis of studies .
 
More details
Hide details
1
Oddział Kliniczny Psychiatrii i Psychoterapii Wieku Rozwojowego, Katedra Psychiatrii i Psychoterapii, Śląski Uniwersytet Medyczny w Katowicach Centrum Pediatrii im. Jana Pawła II w Sosnowcu
2
Akademia Leona Koźmińskiego, Warszawa
CORRESPONDING AUTHOR
Krzysztof Maria Wilczyński   

Oddział Kliniczny Psychiatrii i Psychoterapii Wieku Rozwojowego, Katedra Psychiatrii i Psychoterapii, Śląski Uniwersytet Medyczny w Katowicach Centrum Pediatrii im. Jana Pawła II w Sosnowcu
Submission date: 2020-06-16
Final revision date: 2020-10-24
Acceptance date: 2020-11-29
Online publication date: 2020-12-30
Publication date: 2020-12-30
 
 
KEYWORDS
TOPICS
ABSTRACT
Introduction: Depression is currently the most common mental disorder in the world, and it is estimated that it affects from about 350-840 million people worldwide. The pattern of nutrition observed in the course of depression may be associated with the risk of many nutritional deficiencies, inter allia vitamin D deficiency, which may lead to an increase in symptoms of affective disorders, reduce the effectiveness of treatment and worsen the prognosis. The aim of this study was the identification and summary of studies examining the relationship between vitamin D levels and the risk and symptoms severeity of depression, published between January 2008 and 2019. Methods: A systematic review of literature published within the last 10 years and accessible in PubMed database, was conducted by each author separately based on predetermined inclusion criteria. Results: Out of the 823 studies qualified to the initial abstract analysis, 24 were included into the full-text review and 18 into the meta-analysis. Statistically significant odds ratio was obtained for risk of depression in course of vitamin D deficiency (OR=1,51; 95%CI: 1,4-1,62; p<0.01). Conclusions: The analysis of available literature seems to indicate that there is an association between risk of depression and vitamin D deficiency. However, current literature does not give the possibility to state explicitly what is the exact mechanism and direction of this dependency.
eISSN:2391-5854
ISSN:0033-2674