ARTICLE
The influence of the repetitive transcranial magnetic stimulation on sleep quality in depression
| 1 | Zakład Neurofizjologii Klinicznej, Instytut Psychiatrii i Neurologii, Warszawa |
| 2 | II Klinika Psychiatryczna Instytut Psychiatrii i Neurologii w Warszawie |
| 3 | III Klinika Psychiatryczna, Instytut Psychiatrii i Neurologii, Warszawa |
CORRESPONDING AUTHOR
Jakub Maria Antczak
Zakład Neurofizjologii Klinicznej, Instytut Psychiatrii i Neurologii, ul. Botaniczna 3, 31-503 Kraków, Polska
Zakład Neurofizjologii Klinicznej, Instytut Psychiatrii i Neurologii, ul. Botaniczna 3, 31-503 Kraków, Polska
Submission date: 2016-11-22
Final revision date: 2017-01-10
Acceptance date: 2017-01-15
Online publication date: 2017-10-29
Publication date: 2017-10-29
Psychiatr Pol 2017;51(5):845–857
KEYWORDS
TOPICS
ABSTRACT
Objectives:
Repetitive transcranial magnetic stimulation (rTMS) improves mood in depression. In this study we investigated whether the depression-related insomnia is modulated by this therapeutic method.
Methods:
We examined 13 patients (mean age 50.6±13.9; 11 women) with bipolar or unipolar depression. During 20 consecutive days, excluding Saturdays and Sundays, they underwent 20 daily sessions of 10 Hz rTMS over the left dorsolateral prefrontal cortex (DLPFC). Outcome measurement included the Clinical Global Impression (CGI), the 21item Hamilton Depression Rating Scale (HDRS), the Athens Insomnia Scale (AIS) as well as sleep diary and actigraphy.
Results:
After rTMS, the CGI and HDRS total score decreased significantly. Also, the insomnia-related items of HDRS improved. The AIS showed trend towards decrease. No significant changes were present in sleep diaries and actigraphy.
Conclusions:
The beneficial effect of rTMS on the mood in depression has been confirmed. The rest of the results suggest high frequency rTMS to the left DLPFC does not have strong effects on sleep quality in patients with depression. Additional interventions or modification of the rTMS protocol should be considered to improve insomnia in these patients.
Repetitive transcranial magnetic stimulation (rTMS) improves mood in depression. In this study we investigated whether the depression-related insomnia is modulated by this therapeutic method.
Methods:
We examined 13 patients (mean age 50.6±13.9; 11 women) with bipolar or unipolar depression. During 20 consecutive days, excluding Saturdays and Sundays, they underwent 20 daily sessions of 10 Hz rTMS over the left dorsolateral prefrontal cortex (DLPFC). Outcome measurement included the Clinical Global Impression (CGI), the 21item Hamilton Depression Rating Scale (HDRS), the Athens Insomnia Scale (AIS) as well as sleep diary and actigraphy.
Results:
After rTMS, the CGI and HDRS total score decreased significantly. Also, the insomnia-related items of HDRS improved. The AIS showed trend towards decrease. No significant changes were present in sleep diaries and actigraphy.
Conclusions:
The beneficial effect of rTMS on the mood in depression has been confirmed. The rest of the results suggest high frequency rTMS to the left DLPFC does not have strong effects on sleep quality in patients with depression. Additional interventions or modification of the rTMS protocol should be considered to improve insomnia in these patients.
RELATED ARTICLE
Project no. RCN/SN/0610/2021/1 implemented from 2022 to 2024
Total value of the project: PLN 490 000
Amount funded by the MEiN: PLN 100 000
Aims of the project: Publication in Open Access mode on the Internet of English and Polish language versions of 12 consecutive issues of the journal Psychiatria Polska (years 2022-2024). Modernization and redesign of the journal’s website. Financing of the Editorial System. Copy editing and proofreading of journal issues. Counteracting scientific misinformation. Submission of electronic versions of the journal to the National Digital Library Polona and the Digital Library of Scientific Publications Academica.
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