Large animals as potential models of human mental and behavioral disorders
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I Klinika Psychiatrii w Bydgoszczy, Collegium Medicum w Bydgoszczy, Uniwersytet Mikołaja Kopernika w Toruniu
Zakład Inżynierii Biomedycznej, Uniwersytet Technologiczno-Przyrodniczy w Bydgoszczy
Submission date: 2016-06-14
Final revision date: 2017-03-09
Acceptance date: 2017-06-01
Online publication date: 2017-12-30
Publication date: 2017-12-30
Corresponding author
Michał Danek   

I Klinika Psychiatrii Collegium Medicum w Bydgoszczy UMK w Toruniu, ul. M. Curie Skłodowskiej 9, Uniwersyteckie Centrum Kliniczne, 85-094 Bydgoszcz, Polska
Psychiatr Pol 2017;51(6):1009-1027
Many animal models in different species have been developed for mental and behavioral disorders. This review presents large animals (dog, ovine, swine, horse) as potential models of this disorders. The article was based on the researches that were published in the peer-reviewed journals. Aliterature research was carried out using the PubMed database. The above issues were discussed in the several problem groups in accordance with the WHO International Statistical Classification of Diseases and Related Health Problems 10thRevision (ICD-10), in particular regarding: organic, including symptomatic, disorders; mental disorders (Alzheimer’s disease and Huntington’s disease, pernicious anemia and hepatic encephalopathy, epilepsy, Parkinson’s disease, Creutzfeldt-Jakob disease); behavioral disorders due to psychoactive substance use (alcoholic intoxication, abuse of morphine); schizophrenia and other schizotypal disorders (puerperal psychosis); mood (affective) disorders (depressive episode); neurotic, stress-related and somatoform disorders (posttraumatic stress disorder, obsessive-compulsive disorder); behavioral syndromes associated with physiological disturbances and physical factors (anxiety disorders, anorexia nervosa, narcolepsy); mental retardation (Cohen syndrome, Down syndrome, Hunter syndrome); behavioral and emotional disorders (attention deficit hyperactivity disorder). This data indicates many large animal disorders which can be models to examine the above human mental and behavioral disorders.
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