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ARTICLE
Towards better non-selectivity: the role of 5-HT7 receptors in therapeutic efficacy of a second-generation antipsychotic, lurasidone
 
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1
Zakład Farmakologii
2
Zakład Zaburzeń Afektywnych, Katedra Psychiatrii Collegium Medicum UJ
3
Katedra i Klinika Psychiatrii
CORRESPONDING AUTHOR
Przemysław Bieńkowski   

Zakład Farmakologii, ul. Sobieskiego 9, 02-957 Warszawa, Polska
Submission date: 2015-01-18
Final revision date: 2015-02-05
Acceptance date: 2015-02-05
Publication date: 2015-04-30
 
Psychiatr Pol 2015;49(2):243–253
 
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ABSTRACT
Effectiveness of currently available antipsychotic medications is far from satisfactory with many patients showing incomplete therapeutic response even after many trials with different antipsychotic drugs. Hence, there is an ongoing interest in searching for pharmacological mechanisms, which could potentiate therapeutic response to antipsychotic drugs and/or reduce its typical side effects. The primary aim of this mini-review is to summarize available evidence supporting the role of serotonin receptors, especially 5-HT7 receptors, in therapeutic effects of a second-generation antipsychotic drug, lurasidone.
eISSN:2391-5854
ISSN:0033-2674